LOTENSIN (BENAZEPRIL)
Purpose of medication and method of action: Lotensin is used to treat high blood pressure. It inhibits the action of angiotensin converting enzyme (ACE). This inhibition reduces blood pressure by preventing the formation of Angiotensin II, a biochemical produced by the kidney which increases blood sodium (greater water retention). It is usually used along with other drugs for high blood pressure.

Side Effects: The most common side effects are: dizziness, a persistant cough, fatigue, and nausea. Should the cough become troublesome, contact your physician. Rarely, a condition called angioedema characterized by swelling of the face and hands may occur - if so, call your physician immediately.

Drug Interactions:  If used with potassium sparing diuretics such as triamterene, an increase in blood potassium may result with an adverse effect on the heart. Lotensin may reduce the absorption of the antibiotic tetracycline. The blood level of lithium may be increased by Lotensin and extreme caution should be exercised when Accupril is added to existing lithium therapy.

Cautions and Contraindications: The dose needs to be modified downward if kidney function is impaired.

Usual Dose: Initially, 10 mg each day to a maximum of 20-40 mg daily in two divided doses.