Potential Role of CMV in Restenosis Following Angioplasty, in Atherosclerosis, and in Endothelial Dysfunction

This study is currently recruiting patients.

Sponsored by

National Heart, Lung, and Blood Institute (NHLBI)

bulletPurpose

The purpose of this study is to investigate whether the susceptibility of subjects to atherosclerosis is influenced by prior CMV exposure, whether the susceptability to endothelial dysfunction in patients with and in patients without atherosclerosis is influenced by prior CMV exposure.

Condition

Coronary Disease

Atherosclerosis

Arterial Occlusive Diseases

Cytomegalovirus Infections

Study Type: Natural History

Official Title: Potential Role of CMV in Restenosis Following Angioplasty, in Atherosclerosis, and in Endothelial Dysfunction

Further Study Details: The purpose of this study is to investigate whether the susceptibility of subjects to atherosclerosis is influenced by prior CMV exposure, whether the susceptability to endothelial dysfunction in patients with and in patients without atherosclerosis is influenced by prior CMV exposure.  

bulletEligibility

Genders Eligible for Study:  Both Criteria

Patients who are being evaluated to determine if they have CAD or those who have already been studied and the presence or absence of CAD has been ascertained.

No patients who have not been evaluated for CAD.

bulletLocation and Contact Information

Maryland

National Heart, Lung and Blood Institute (NHLBI), 9000 Rockville Pike   Bethesda,   Maryland,    20892,   United States; Recruiting

PRPL     Warren G. Magnuson Clinical Center National Institutes of Health   Bethesda,    Maryland,   20892-4754,   United States  1-800-411-1222    prpl@mail.cc.nih.gov  

bulletMore Information

Detailed Web Page

Publications that lead up to this study

Speir. 1994. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis, Science, Vol. 265, p. 391

Schrier. 1995. Immuno Predispositions for cytomegalovirus Retinitis in AIDS, J Clin Invest, Vol. 95, p. 1741

Study ID Numbers  96-H-0099

NLM Identifier  NCT00001531

Date study started June 6, 1996

Recruitment status verified  August 27, 1999

 

Last Updated  August 27, 1999

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